About Us
The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research program at the University of Oxford. The OPDC was established in February 2010 and brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.
Our world-class research centre works to understand the earliest events in the development of Parkinson’s with an ultimate view to target the molecular mechanisms of disease with neuroprotective therapies to prevent disease onset or delay progression.
Our program is focused on the molecular pathways to Parkinson’s in order to:
- Understand the progression of Parkinson’s
- Predict the onset of Parkinson’s
- Identify potential drug targets for Parkinson’s
- Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
Watch the video below to learn more about OPDC's research:
Latest News
Upcoming Seminars
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Wednesday, 08 May 2024, 12pm to 1pm
Latest publications
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Automated quality control of T1-weighted brain MRI scans for clinical research: methods comparison and design of a quality prediction classifier
Preprint
Bhalerao GV. et al, (2024)
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Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation.
Journal article
Do QB. et al, (2024), NPJ Parkinsons Dis, 10
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RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses.
Journal article
Gustavsson EK. et al, (2024), Lancet Neurol
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Motor Complications in Parkinson's Disease: Results from 3343 Patients Followed for up to 12 Years.
Journal article
Gandhi SE. et al, (2024), Mov Disord Clin Pract
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Distributional coding of associative learning in discrete populations of midbrain dopamine neurons
Journal article
Avvisati R. et al, (2024), Cell Reports, 43, 114080 - 114080
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CRISPRi: a way to integrate iPSC-derived neuronal models
Journal article
Franks SNJ. et al, (2024), Biochemical Society Transactions