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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

Oxford Parkinson's Disease Centre members raise funds for their research and enjoy a pub quiz in the process!

Oxford Parkinson's Disease Centre members raise funds for their research and enjoy a pub quiz in the process!

Posted 03/01/2019

Parkinson’s researchers Dayne Beccano-Kelly, Siv Vingill and Nora Bengoa-Vergniory, along with OPDC administrator Melanie Witt travelled to the Royal Oak, Goodworth Clatford in Andover for a quiz night in aid of Parkinson’s research. During the night, held on Wednesday 12 December, OPDC supporters Bobbie Coelho, Mary Doherty and Dawn Huntly presented a cheque for £1,500 to support Parkinson’s research. The funds have been raised by a number ...


OPDC research featured in OxfordAI videos

OPDC research featured in OxfordAI videos

Posted 21/12/2018

The videos focus on two of our projects to use new technology to better understand the progression of Parkinson's. The first highlights our sleep study which aims to make it possible to monitor sleep in the home using wearable devices. The second features our smartphone app which monitors different motor symptoms of Parkinson's to improve our understanding of Parkinson's and help us improve treatments.    


Sleep study seeks people with Parkinson's and/or RBD

Sleep study seeks people with Parkinson's and/or RBD

Posted 14/11/2018

Researchers at OPDC are embarking on a new five-year study looking at the links between a condition known as Rapid Eye Movement Sleep Behaviour Disorder (RBD) and Parkinson’s. Funded by the NIHR Oxford Biomedical Research Centre. The study seeks to improve the remote diagnosis and monitoring of sleep problems at home and is currently looking for people with Parkinson's and RBD to take part. RBD is a sleep problem where the switch that ...

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Seminars/Events

Elisa Greggio 13 Feb 2019

Elisa Greggio 13 Feb 2019

Posted 27/11/2018

Molecular pathways to Parkinson's disease: more than neurons? Dr. Elisa Greggio is a molecular physiologist in the Department of Biology at the University of Padova, Italy. RESEARCH INTERESTS: Genetic forms of dominant Parkinson's.Mitochondrial function, axonal transport and cellular pathways in Parkinson's.Biochemical properties of Leucine-rich repeat kinase 2 (LRRK2).Oxidative stress in ...

Kirsten Harvey 27 Mar 2019

Kirsten Harvey 27 Mar 2019

Posted 27/11/2018

LRRK2 Mediated Cellular Function from Vesicular Trafficking to Gene Expression. My research has focused on two main aspects of neurobiology, the pathogenesis of Parkinson’s and trapping and accumulation of inhibitory receptors at synapses. In my laboratory, we employ cell biological, biochemistry and proteomic techniques in an effort to: i) discover how pathogenic mutations in PARK genes lead to neuronal death, ii) uncover new leads for ...

 

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